Precision Medicine
by Jenna Ogilvie | Dec 10, 2018 | Commentary, Perspectives
Heterogeneous responses to the same therapy among individual patients are commonplace in both biomedical research and patient care. Despite being considered by many as the pinnacle of the evidence-based medicine hierarchy, parallel group randomized clinical...
by Jenna Ogilvie | Dec 3, 2018 | Discussion Paper, Perspectives
The central idea of early disease detection and treatment is essentially simple. However, the path to its successful achievement (on the one hand, bringing to treatment those with previously undetected disease, and, on the other, avoiding harm to those...
by Laura DeStefano | Mar 19, 2018 | Discussion Paper, Perspectives
Emerging Opportunities for Digital Health Digital health technologies have emerged in recent years, providing opportunities for engaging with consumers and integrating with the health care system to realize precision medicine, defined as “an evidence-based...
by Jenna Ogilvie | Sep 19, 2016 | Discussion Paper, Perspectives
About the Vital Directions for Health and Health Care Series This publication is part of the National Academy of Medicine’s Vital Directions for Health and Health Care Initiative, which commissioned expert papers on 19 priority focus areas for U.S. health policy by...
by Jenna Ogilvie | Feb 2, 2016 | Commentary, Perspectives
In early 2015, President Obama announced a $215 million investment in the 2016 budget to revolutionize health improvement efforts and disease treatment. The Precision Medicine Initiative (PMI) is a new model of patient-powered research using big data to...
by Jenna Ogilvie | Jun 22, 2015 | Discussion Paper, Perspectives
The types of evidence needed to support the use of genome sequencing in the clinic varies by stakeholder and circumstance. In this IOM series, seven individually authored commentaries explore this important issue, discussing the challenges involved in and...
by Jenna Ogilvie | Feb 5, 2015 | Discussion Paper, Perspectives
The types of evidence needed to support the use of genome sequencing in the clinic varies by stakeholder and circumstance. In this IOM series, seven individually authored commentaries explore this important issue, discussing the challenges involved in and...
by Jenna Ogilvie | Jan 15, 2015 | Discussion Paper, Perspectives
The types of evidence needed to support the use of genome sequencing in the clinic varies by stakeholder and circumstance. In this IOM series, seven individually authored commentaries explore this important issue, discussing the challenges involved in and...
by Laura DeStefano | Dec 14, 2012 | Commentary, Perspectives
We have a good concept of the flawed state of health care, the critical need for change, and the future we want. Patient-centered, personalized care, provided by collaborating care teams, is a part of that vision. Many changes will be necessary to achieve that future,...
by Laura DeStefano | Oct 5, 2012 | Commentary, Perspectives
My story of innovation begins in 1981, when, as a young surgical trainee in Boston, I was shocked to learn that my dreams of joining the pioneers in the exciting new field of heart transplantation had been abruptly shattered—by a policy decision. The trustees of the...
