Biomedical Science and Research
by Jenna Ogilvie | Sep 30, 2019 | Discussion Paper, Perspectives
Introduction Cell-, gene-, and tissue-based advanced therapeutic products, referred to in this paper as “cell and gene therapy” (CGT) products, have the potential to address many unmet medical needs. These products are commonly discovered and developed in...
by Jenna Ogilvie | Jul 1, 2019 | Commentary, Perspectives
An Evolving Global Age Distribution and New Implications for Social Cognition and Interpersonal Trust In the years to come, there will be a significant global increase in the number of older adult persons. Some projections indicate that by 2030, there will be a...
by Jenna Ogilvie | Jul 1, 2019 | Discussion Paper, Perspectives
The National Academy of Medicine (NAM) has prioritized the use of clinical and administrative health care data as a core utility for a continuously learning health system (The “Learning Health System” is a system in which science, informatics, incentives, and...
by Jenna Ogilvie | Dec 17, 2018 | Discussion Paper, Perspectives
Introduction Breast cancer is the most common malignancy among women in the United States, with over 260,000 new cases and over 40,000 deaths estimated to occur in 2018 [1]. Although most breast cancers are diagnosed with disease localized to the breast or...
by Jenna Ogilvie | Dec 10, 2018 | Commentary, Perspectives
Heterogeneous responses to the same therapy among individual patients are commonplace in both biomedical research and patient care. Despite being considered by many as the pinnacle of the evidence-based medicine hierarchy, parallel group randomized clinical...
by Jenna Ogilvie | Dec 3, 2018 | Discussion Paper, Perspectives
The central idea of early disease detection and treatment is essentially simple. However, the path to its successful achievement (on the one hand, bringing to treatment those with previously undetected disease, and, on the other, avoiding harm to those...
by Jenna Ogilvie | Nov 19, 2018 | Commentary, Perspectives
Introduction On January 14, 2015, the Institute of Medicine (IOM) released a consensus study report titled Sharing Clinical Trial Data: Maximizing Benefits, Minimizing Risk [1], which detailed guiding principles and a practical framework for responsibly...
by Jenna Ogilvie | Oct 22, 2018 | Commentary, Perspectives
Controlling or reducing the risk for cancer was a principal goal of the National Cancer Act, signed by President Nixon in 1971. Long before the human genome was sequenced, and the etiology of many cancers was understood, Americans were determined to find a way...
by Jenna Ogilvie | Oct 1, 2018 | Discussion Paper, Perspectives
Introduction The person-centered health information system (PCHIS) of the future leverages information technology enhanced by artificial intelligence (AI) to support better, safer, and more affordable health care. The vision presented in this paper describes a...
by Jenna Ogilvie | Oct 1, 2018 | Commentary, Perspectives
Upon arriving in Kenya in 1987, I was a well-trained parasitologist who knew nothing about development, economics, political systems, or structural poverty. Kenya, however, became my classroom. The focus three decades ago was to attack one disease at a time, to...
Page 3 of 8«12345...»Last »
