This meeting will formally announce the release of the Roundtable on Value & Science-Driven Health Care workshop summary, Digital Infrastructure for the Learning Health System: The Foundation for Continuous Improvement in Health and Health Care. In addition, there will be an opportunity to review issues, priorities, and opportunities outlined in the report, and discuss priorities and opportunities for progress. This report is a summary of the Digital Infrastructure for the Learning Healthcare System workshop series, sponsored by the Office of the National Coordinator for Health Information Technology.